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Protected Data Pipelines Start with Self-Sovereign Control 

Built to meet the requirements of HIPAA, GDPR, CCPA, and other global privacy regulations. 

Most de-identification tools serve a narrow purpose, leading to a dead end for broader use across your workflow. 

Karlsgate was built to go further—creating Protected Data Pipelines that ensure secure utility across your data’s lifecycle. 

With de-identification designed for maximum match quality, protection at every stage, self-sovereign control, and automation to scale your workflows, Karlsgate delivers data that’s usable and protected on your terms.

Karlsgate turns de-identification into the launchpad that keeps your data moving safely from storage to insight to impact. 

It starts with free tools for self-sovereign de-identification, because protection should be a shared standard, not a proprietary advantage. 

From there, you can perform secure collaboration and integrate protected outputs directly into your workflows. 

With Karlsgate, you can...

Prevent your sensitive data from being exposed while in use

Replace raw identifiers with Cryptonyms (locally encrypted codes) that remain under your exclusive control. Karlsgate’s self-sovereign de-identification protects your data at the source while enabling research-grade matching and downstream use. It’s the first step toward creating protected data pipelines. 

Share limited information with others while maintaining full control

Collaborate across organizations without exposing raw identifiers or persistent pseudonyms. Whether your data starts with PII or Cryptonyms, Karlsgate transforms it into single-use matching keys—generated separately by each party and compared by an independent process that can never reveal the underlying identity. 

Navigate tech stacks without switching protective tools sets

Karlsgate's integration tools were designed to securely bring together data from different environments and enable individual-level linkage without exposing sensitive identifiers. You can push or pull selected data across environments without ever exchanging clear text, persistent pseudonyms, or secret keys.  

Don’t just restrict access.
Protect data while it keeps working. 

 

"The overlap analysis process for evaluating new partners, fraught with big data and compliance challenges, has been streamlined significantly thanks to our collaboration with Karlsgate. This partnership has allowed Eyeota to evaluate potential new data partnerships – without either party having to physically transfer data – more efficiently and bring new data assets to market more quickly." 

 

Jess Saunders, VP, Global Partner Success 

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Resource Center

Insights from Karlsgate Thought Leaders

DOGE, Clean Rooms, and the Data Centralization Dilemma

DOGE, Clean Rooms, and the Data Centralization Dilemma

Why Pooling Sensitive Data Isn't The Answer To Effective Collaboration

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April 14, 2025

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Why Modern Data Workflows Require a New Approach to Control

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Data Security